Sheena's parents were archaeologists who died in the jungle when she was about six years old, leaving their daughter Shirley Hamilton. She was taken in by Kali, a local Shamaness of a tribe who brought her up, and five years ago she was taught how to morph into animals and birds, acquiring their abilities, even flight. Further, she became a mythical creature called "The Darachna" who relies on people' fear of the unknown. For this she covers herself in a dark liquid mud which allows her to be largely unseen in the low light of the jungle, and with more than normal strength, agility and speed, and armed with a pair of gloves with bone claws, she is a formidable one woman fighting force. She does kill sometimes.

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The adventures of the cosmic wanderer as he seeks his lost home after rebelling from his master.