Remy is a medical student who has a flair for making his patients comfortable. His genuine concern for the patients in his charge marks him as a hot prospect in his internship program. Pamela works at a children's book publishing company. The two meet via Pamela's brother, who is also Remy's good friend. They fall in love and get an apartment in the East Village of New York. Soon after, the couple begins to indulge in speed and barbiturates. They become heavily addicted. Remy is thrown out of medical school and Pamela quits her job. Remy soon finds himself in debt with the local dealer, Stutter, who introduces his customer to heroin as a revenge for his late bill. Pamela faces the prospect of getting sober at her brother's clinic, but must leave behind a destitute Remy in order to do it.

When illegal card dealer and recovering heroin addict Frankie Machine gets out of prison, he decides...

A transgender woman takes an unexpected journey when she learns that she had a son, now a teenage ru...

The brief life of Jean Michel Basquiat, a world renowned New York street artist struggling with fame...

A ticking-time-bomb insomniac and a slippery soap salesman channel primal male aggression into a sho...

Wyatt and Billy, two Harley-riding hippies, complete a drug deal in Southern California and decide t...

Heroin addict Mark Renton stumbles through bad ideas and sobriety attempts with his unreliable frien...

People in the future live in a totalitarian society. A technician named THX 1138 lives a mundane lif...

The drug-induced utopias of four Coney Island residents are shattered when their addictions run deep...

A logger defends his family from a group of dangerous drug runners.

Rick (Rutger Hauer), a disaffected sailor turned hard drinking womanizer, returns home from six mont...
17-year-old track star, John Owens, has never used any drug stronger than pot, until he meets an old...

New York comedian Alvy Singer falls in love with the ditsy Annie Hall.

A young street hustler attempts to escape the rigors and temptations of the ghetto in a quest for a ...

In 1987, five young men, using brutally honest rhymes and hardcore beats, put their frustration and ...

Good policing doesn't necessarily mean doing everything by the book. But as the business of crime in...

A New York nightclub manager tries to save his brother and father from Russian mafia hitmen.

On his first day on the job as a narcotics officer, a rookie cop works with a rogue detective who is...

A drug pusher grows increasingly desperate after a botched deal leaves him with a large debt to a ru...

A psychological study of the effects of drug addiction on humanity. Helene Ford has been injected wi...

In 1950s Mexico City, William Lee, an American ex-pat in his late forties, leads a solitary life ami...