Remy is a medical student who has a flair for making his patients comfortable. His genuine concern for the patients in his charge marks him as a hot prospect in his internship program. Pamela works at a children's book publishing company. The two meet via Pamela's brother, who is also Remy's good friend. They fall in love and get an apartment in the East Village of New York. Soon after, the couple begins to indulge in speed and barbiturates. They become heavily addicted. Remy is thrown out of medical school and Pamela quits her job. Remy soon finds himself in debt with the local dealer, Stutter, who introduces his customer to heroin as a revenge for his late bill. Pamela faces the prospect of getting sober at her brother's clinic, but must leave behind a destitute Remy in order to do it.

When illegal card dealer and recovering heroin addict Frankie Machine gets out of prison, he decides...

A transgender woman takes an unexpected journey when she learns that she had a son, now a teenage ru...

The brief life of Jean Michel Basquiat, a world renowned New York street artist struggling with fame...

A ticking-time-bomb insomniac and a slippery soap salesman channel primal male aggression into a sho...

Wyatt and Billy, two Harley-riding hippies, complete a drug deal in Southern California and decide t...

Heroin addict Mark Renton stumbles through bad ideas and sobriety attempts with his unreliable frien...

Raoul Duke and his attorney Dr. Gonzo drive a red convertible across the Mojave desert to Las Vegas ...

An exploration of the United States of America's war on drugs from multiple perspectives. For the ne...

Frustrated, because he is forced to produce bad TV-shows, a manager of a TV-station, enters the stat...

In the questionable town of Deer Meadow, Washington, FBI Agent Desmond inexplicably disappears while...

A New York nightclub manager tries to save his brother and father from Russian mafia hitmen.

On his first day on the job as a narcotics officer, a rookie cop works with a rogue detective who is...

A drug pusher grows increasingly desperate after a botched deal leaves him with a large debt to a ru...

A young street hustler attempts to escape the rigors and temptations of the ghetto in a quest for a ...

After his friend, a hot young artist, is killed, a resourceful American man living in London covers ...

A newly elected District attorney finds himself in the middle of a police corruption investigation t...

An ex-marine who struggles to provide for his family and a violent drug dealer with an undefeated fi...

23-year old Sandra has been doing drugs for many years and has realized that she is in need of some ...

Maggie lives with chronic pain and is having a crisis of faith. To cope, she abuses her elderly moth...

Inspired by the true story of Greg Yance. In the film, Yance (Epps) is a hood who goes to jail for p...