Remy is a medical student who has a flair for making his patients comfortable. His genuine concern for the patients in his charge marks him as a hot prospect in his internship program. Pamela works at a children's book publishing company. The two meet via Pamela's brother, who is also Remy's good friend. They fall in love and get an apartment in the East Village of New York. Soon after, the couple begins to indulge in speed and barbiturates. They become heavily addicted. Remy is thrown out of medical school and Pamela quits her job. Remy soon finds himself in debt with the local dealer, Stutter, who introduces his customer to heroin as a revenge for his late bill. Pamela faces the prospect of getting sober at her brother's clinic, but must leave behind a destitute Remy in order to do it.

In 1973, 15-year-old William Miller's unabashed love of music and aspiration to become a rock journa...

Slaking a thirst for dangerous games, Kathryn challenges her stepbrother, Sebastian, to deflower the...

When illegal card dealer and recovering heroin addict Frankie Machine gets out of prison, he decides...

A transgender woman takes an unexpected journey when she learns that she had a son, now a teenage ru...

The brief life of Jean Michel Basquiat, a world renowned New York street artist struggling with fame...

Wyatt and Billy, two Harley-riding hippies, complete a drug deal in Southern California and decide t...

Heroin addict Mark Renton stumbles through bad ideas and sobriety attempts with his unreliable frien...

People in the future live in a totalitarian society. A technician named THX 1138 lives a mundane lif...

The drug-induced utopias of four Coney Island residents are shattered when their addictions run deep...

In the 1800s, a stormy love relationship develops quickly between a young medical student and a woma...

Lured by their dreams of fame and fortune, three ambitious young women enter the world of show busin...

A young boy takes interest in piano while his family begins to disintegrate around him after his fat...

Friday, 11 p.m. Carla, a woman in her forties, is alone in her office. She gets a call. It's Raúl, a...

A young street hustler attempts to escape the rigors and temptations of the ghetto in a quest for a ...

This is the story of Isa, who grows up in a Hamburg suburb. It might be one of the world's richest c...

After her drug pusher boyfriend overdoses on heroin, a cabaret singer finds refuge from the authorit...

A taxi driver kicks a homeless woman out of his car. It'll be a long night until he can make amends.

Craig and Smokey are two guys in Los Angeles hanging out on their porch on a Friday afternoon, smoki...

A man against capital punishment is accused of murdering a fellow activist and is sent to death row.

Spring 1995 - after the closure of the Needle Park and the public drug scene in Zurich, eleven-year-...