Remy is a medical student who has a flair for making his patients comfortable. His genuine concern for the patients in his charge marks him as a hot prospect in his internship program. Pamela works at a children's book publishing company. The two meet via Pamela's brother, who is also Remy's good friend. They fall in love and get an apartment in the East Village of New York. Soon after, the couple begins to indulge in speed and barbiturates. They become heavily addicted. Remy is thrown out of medical school and Pamela quits her job. Remy soon finds himself in debt with the local dealer, Stutter, who introduces his customer to heroin as a revenge for his late bill. Pamela faces the prospect of getting sober at her brother's clinic, but must leave behind a destitute Remy in order to do it.

Marcello, a small and gentle dog groomer, finds himself involved in a dangerous relationship of subj...

A friendly, successful suburban teacher and father grows dangerously addicted to cortisone, resultin...

Teenage gang member Cal, hides his sexuality from his fellow gang members despite their often violen...

Kaisa is a Scot, a successful London lawyer, who snorts coke and has one-night stands with strangers...

Erin and Garrett are very much in love. When Erin moves to San Francisco to finish her journalism de...

High-school principal Dr. Alfred Carroll relates to an audience of parents that marijuana can have d...

Over the course of one night, a woman drives across LA with her heroin addict brother in search of a...

Cliff receives an unusual 18th birthday gift from his younger sister — marijuana, alcohol, a subway ...

Four young heroin addicts scour the streets of Melbourne in search of some good-quality narcotics – ...

Fudo is a drug addict who decides to quit heroin and reconcile with his mother after his best friend...
Before we can join society as productive and acceptable human beings, we are forced to endure a diff...
Sammy is a teenage cutter living with her meth addicted mother in a trailer on the Indian Ridge Rese...

The wife of an executive finds her husband shot to death and destroys his suicide note in order to c...

Thomas is a drug addict. In an effort to put an end to his habit, he joins a community of former add...

Dave is a bad cop fighting a deadly heroin addiction while working a case deep inside the mafia. Aft...

A young drug-addled writer approaching the bottom of his descent submits to two months of agonizing ...

When Syd, a young editor at an influential art magazine, becomes involved with her neighbor, a drug...

A short, unhappy affair with a married man leads a dedicated schoolteacher into the alcohol-and-drug...

Konrad von Seidlitz is a young yuppie lawyer currently celebrating his engagement with Cornelia, dau...

In a seaside California town, best friends Mac and Nick are on opposite sides of the law. Mac is a f...